Aging Cell Best Paper Prize

Aging Cell Best Paper Prize

Aging Cell Best Paper Prize

Background

Awarded by the Society on the recommendation of the EiCs to the Lead Author and Co-Authors. This is awarded annually for the paper considered to be the most outstanding published (or accepted for publication) in Aging Cell in that year by either a member or non-member of the Society. For further information contact the Executive Administrator at: headoffice@anatsoc.org.uk

Eligibility

Member or non-member of the Society

Awarded

Annually

Queries

For further information contact the Executive Administrator at: headoffice@anatsoc.org.uk

To be awarded in 2026

Aging Cell Best Paper Award

The SATB1-MIR22-GBA axis mediates glucocerebroside accumulation inducing a cellular senescence-like phenotype in dopaminergic neurons

Taylor RussoBenjamin KolisnykAswathy B. S.Jonathan Plessis-BelairTae Wan KimJacqueline MartinJason NiJordan A. PearsonEmily J. ParkRoger B. SherLorenz StuderMarkus Riessland

Aging Cell, Vol23, Issue 4, April 2024

https://onlinelibrary.wiley.com/doi/10.1111/acel.14077


Aging Cell Joint Runner-Up Best Paper Award

A molecular index for biological age identified from the metabolome and senescence-associated secretome in humans

Shruthi HamsanathanTamil AnthonymuthuDenise ProsserAnna LokshinSusan L. GreenspanNeil M. ResnickSubashan PereraSatoshi OkawaGiri NarasimhanAditi U. Gurkar

Aging Cell, Vol 23, Issue 4, April 2024

https://onlinelibrary.wiley.com/doi/10.1111/acel.14104

                                         AND

Alterations of the gut microbiome are associated with epigenetic age acceleration and physical fitness

Ferenc TormaCsaba KerepesiMátyás JókaiGergely BabszkiErika KoltaiBalázs LigetiRegina KalcsevszkiKristen M. McGreevySteve HorvathZsolt Radák

Aging Cell, Vol 23, Issue 4, April 2024

https://onlinelibrary.wiley.com/doi/10.1111/acel.14101

Aging Cell Best Paper Prize

Antiretroviral protease inhibitors induce features of cellular senescence that are reversible upon drug removal

Chisaka Kuehnemann, Jun-Wei B Hughes, Pierre-Yves Desprez, Simon Melov, Christopher D Wiley, Judith Campisi

Aging Cell, Vol 22, Issue 1, January 2023

Article ID: e13750

https://pubmed.ncbi.nlm.nih.gov/36539941/



Aging Cell Runner-Up Best Paper Prize

 

Calorie restriction modulates the transcription of genes related to stress response and longevity in human muscle: The CALERIE study

Jayanta Kumar Das, Nirad Banskota, Julián Candia, Michael E Griswold, Melissa Orenduff, Rafael de Cabo, David L Corcoran, Sai Krupa Das, Supriyo De, Kim Marie Huffman, Virginia B Kraus, William E Kraus, Corby K Martin, Susan B Racette, Leanne M Redman, Birgit Schilling, Daniel W Belsky, Luigi Ferrucci

Aging Cell, Vol 22, Issue 12, December 2023

Aging Cell Best Paper Award


Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1-imidazoline receptor

Dominic F. Bennett, Anita Goyala, Cyril Statzer, Charles W. Beckett, Alexander Tyshkovskiy, Vadim N. Gladyshev, Collin Y. Ewald, João Pedro de Magalhães

Aging Cell, Volume 22, Issue 2, February 2023, Pages 1-15

Accepted Dec 09, 2022. First published: 20 January 2023

https://doi.org/10.1111/acel.13774



Aging Cell Runner-Up Best Paper Award

A single short reprogramming early in life initiates and propagates an epigenetically related mechanism improving fitness and promoting an increased healthy lifespan

Quentin Alle, Enora Le Borgne, Paul Bensadoun, Camille Lemey, Nelly Béchir, Mélissa Gabanou, Fanny Estermann, Christelle Bertrand-Gaday, Laurence Pessemesse, Karine Toupet, Romain Desprat, Jérôme Vialaret, Christophe Hirtz, Danièle Noël, Christian Jorgensen, François Casas, Ollivier Milhavet, Jean-Marc Lemaitre

Aging Cell, Volume 21, Issue 11, November 2022, Pages 1-12

Accepted Aug 31, 2022. First published: 17 October 2022

https://doi.org/10.1111/acel.13714

Aging Cell Best Paper Prize

 

Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice

Mikolaj Ogrodnik, Shane A. Evans, Edward Fielder, Stella Victorelli, Patrick Kruger, Hanna Salmonowicz, Bettina M. Weigand, Ayush D. Patel, Tamar Pirtskhalava, Christine L. Inman, Kurt O. Johnson, Stephanie L. Dickinson, Azucena Rocha, Marissa J. Schafer, Yi Zhu, David B. Allison, Thomas von Zglinicki, Nathan K. LeBrasseur, Tamar Tchkonia, Nicola Neretti, João F. Passos, James L. Kirkland, Diana Jurk

Aging Cell, Volume 20, Issue 2, February 2021, Pages 1-16

First published 20 January 2021 https://doi.org/10.1111/acel.13296

 

Aging Cell Joint Runner-Up Best Paper Prize

DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the DAMA study

Giovanni Fiorito, Saverio Caini, Domenico Palli, Benedetta Bendinelli, Calogero Saieva, Ilaria Ermini, Virginia Valentini, Melania Assedi, Piera Rizzolo, Daniela Ambrogetti, Laura Ottini, Giovanna Masala

Aging Cell, Volume 20, Issue 10, October 2021, Pages 1-13

First published 18 September 2021 https://doi.org/10.1111/acel.13439

“Protein aggregates” contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation

Robert J. Shmookler  Reis, Ramani Atluri, Meenakshisundaram Balasubramaniam, Jay Johnson, Akshatha Ganne, Srinivas Ayyadevara

Aging Cell, Volume 20, Issue 5, May 2021, Pages 1-20

First published 31 March 2021 https://doi.org/10.1111/acel.13326

 

Best Paper

Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice

Matthew J. Yousefzadeh, Jing Zhao, Christina Bukata, Erin A. Wade, Sara J. McGowan, Luise A. Angelini, Michael P. Bank, Aditi U. Gurkar, Collin A. McGuckian, Mariah F. Calubag, Jonathan I. Kato, Christin E. Burd, Paul D. Robbins, Laura J. Niedernhofer

Aging Cell, Volume 19, Issue 3, March 2020, Pages 1-13

https://doi.org/10.1111/acel.13094

Runner-Up Best Paper Prize

AMPK-mediated formation of stress granules is required for dietary restriction induced longevity in Caenorhabditis elegans

Chen-Ting Kuo, Guan-Ting You, Ying-Jie Jian,Ting-Shin Chen, Yu-Chen Siao, Ao-Lin Hsu, Tsui-Ting Ching

Aging Cell Volume 19, Issue 6, June 2020, Pages 1-12

https://doi.org/10.1111/acel.13157

[Dr Kuo and Dr You are Joint Lead Authors]

Aging Cell Best Paper Prize

Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity

Nelly Olova, Daniel J. Simpson, Riccardo E. Marioni,  Tamir Chandra

Aging Cell, Volume 18, Issue 1, February 2019

Aging Cell. 2019;18:e12877   https://doi.org/10.1111/acel.12877



Aging Cell Joint Runner-Up Best Paper Prize

e12914 Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a

So-Jin Kim, Peiying Shan, Cheol Hwangbo, Yi Zhang, Jin-Na Min, Xuchen Zhang
Taylor Ardito, Alfred Li, Tien Peng, Maor Sauler, Patty J. Lee

Aging Cell, Volume 18, Issue 3, June 2019

Aging Cell. 2019;18:e12914     https://doi.org/10.1111/acel.12914

                                              and  

e12971 Restored immune cell functions upon clearance of senescence in the irradiated splenic environment

Lina Palacio, Marie-Lyn Goyer, Damien Maggiorani, Andrea Espinosa, Norbert Villeneuve, Sara Bourbonnais, Gaël Moquin-Beaudry, Oanh Le, Marco Demaria,
Albert R. Davalos, Hélène Decaluwe, Christian Beauséjour 

Aging Cell, Volume 18, Issue 4, August 2019

Aging Cell. 2019;18:e12971     https://doi.org/10.1111/acel.12971

                                              and

 

e13041 A human tissue-specific transcriptomic analysis reveals a complex relationship between aging, cancer, and cellular senescence

Kasit Chatsirisupachai, Daniel Palmer, Susana Ferreira, João Pedro de Magalhães

Aging Cell, Volume 18, Issue 6, December 2019 

Aging Cell. 2019;18:e13041  https://doi.org/10.1111/acel.13041

Aging Cell Best Paper Prize 2018

Replacement of microglia in the aged brain reverses cognitive, synaptic and neuronal deficits in mice

Monica R. P. Elmore, Lindsay A. Hohsfield, Enikö A. Kramár, Lilach Soreq, Rafael J. Lee, Stephanie T. Pham, Allison R. Najafi, Elizabeth E. Spangenberg, Marcelo A. Wood, Brian L. West, Kim N. Green

Aging Cell, Volume 17, Issue 6, December 2018, Pages 12832-12846

Aging Cell Best Paper Prize 2017

Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion

Kristen M. Stearns-Reider, Antonio D’Amore, Kevin Beezhold, Benjamin Rothrauff, Loredana Cavalli, William R. Wagner, David A. Vorp, Alkiviadis Tsamis, Sunita Shinde,
Changqing Zhang, Aaron Barchowsky, Thomas A. Rando, Rocky S. Tuan, Fabrisia Ambrosio

Volume 16, Issue 3, pages 518-528, June 2017

 

Aging Cell Joint Runner-Up Best Paper Prize 2017

Expansion of myeloid-derived suppressor cells with aging in the bone marrow of mice through a NF-κB-dependent mechanism 

Rafael R. Flores, Cheryl L. Clauson, Joonseok Cho, Byeong-Chel Lee, Sara J. McGowan, Darren J. Baker, Laura J. Niedernhofer, Paul D. Robbins

Volume 16, Issue 3, pages 480-487, June 2017

Translation fidelity coevolves with longevity

Zhonghe Ke, Pramit Mallik, Adam B. Johnson, Facundo Luna, Eviatar Nevo, Zhengdong D. Zhang, Vadim N. Gladyshev, Andrei Seluanov and Vera Gorbunova

Volume 16, Issue 5, pages 988-993, October 2017

Aging Cell Best Paper Prize 2016

Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: ‘reverse’ antagonistic pleiotropy?

Basisty, N., Dai, D.-F., Gagnidze, A., Gitari, L., Fredrickson, J., Maina, Y., Beyer, R. P., Emond, M. J., Hsieh, E. J., MacCoss, M. J., Martin, G. M. and Rabinovitch, P. S.

Volume 15, Issue 4, pages 634–645, August 2016

 Dr Nathan Basisty

Dr Adam Taylor presenting Dr Nathan Basisty with his Aging Cell  Best Paper Prize 2016 Certificate at the AS Winter Meeting, Dundee, 2017

Aging Cell Runner-Up Best Paper Prizes 2016

Mitochondrial metabolites extend lifespan

Mishur,R. J., Khan, M., Munkácsy, E., Sharma, L., Bokov, A., Beam, H., Radetskaya, O., Borror, M., Lane, R., Bai, Y. and Rea, S. L. 

Volume 15, Issue 2, pages 336-348, April 2016

 

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of antiapoptotic factors

Zhu, Y., Tchkonia, T., Fuhrmann-Stroissnigg, H., Dai, H. M., Ling, Y. Y., Stout, M. B., Pirtskhalava, T., Giorgadze, N., Johnson, K. O., Giles, C. B., Wren, J. D., Niedernhofer, L. J., Robbins, P. D. and Kirkland, J. L. 

Volume 15, Issue 3, pages 428-435, June 2016

Aging Cell Best Paper Prize 2015

‘Acceleated epigenetic aging in Down syndrome’
Horvath, S., Garagnani, P., Bacalini, M. G., Pirazzini, C., Salvioli, S., Gentilini, D., Di Blasio, A. M., Giuliani, C., Tung, S., Vinters, H. V. and Franceschi, C.

Aging Cell, Volume 14, Issue 3, June 2015, pages 491-495

 

Aging Cell Runner-Up Best Paper Prizes 2015

‘A peroxiredoxin, PRDX-2, is required for insulin secretion and insulin/IIS-dependent regulation of stress resistance and longevity’

Oláhová, M. and Veal, E. A.  

Aging Cell, Volume 14, Issue 4,  August 2015, pages 558–568

‘The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs’ 
Zhu, Y., Tchkonia, T., Pirtskhalava, T., Gower, A. C., Ding, H., Giorgadze, N., Palmer, A. K., Ikeno, Y., Hubbard, G. B., Lenburg, M., O’Hara, S. P., LaRusso, N. F., Miller, J. D., Roos, C. M., Verzosa, G. C., LeBrasseur, N. K., Wren, J. D., Farr, J. N., Khosla, S., Stout, M. B., McGowan, S. J., Fuhrmann-Stroissnigg, H., Gurkar, A. U., Zhao, J., Colangelo, D., Dorronsoro, A., Ling, Y. Y., Barghouthy, A. S., Navarro, D. C., Sano, T., Robbins, P. D., Niedernhofer, L. J. and Kirkland, J. L. 

Aging Cell, Volume 14, Issue 4,  August 2015, pages 644–658

Aging Cell Best Paper Prize 2014

'Altered proteome turnover and remodelling by short-term caloric restriction or rapamycin rejuvenate the aging heart’ 

D.-F. Dai,P. P. Karunadharma, Y. A. Chiao, N. Basisty, D. Crispin, E. J. Hsieh, T. Chen, H. Gu, D. Djukovic, D. Raftery, R. P. Beyer, M. J. Maccoss, P. S. Rabinovitch

Aging Cell, Volume 13, Issue 3, June 2014, Pages 529–539

Dr. Dai

Dr. Dai receives his award from President Prof. T. Clive Lee at the Winter Meeting of the Society in Cambridge

Aging Cell Runner-Up Best Paper Prizes 2014

‘Growth hormone signaling is necessary for lifespan extension by dietary methionine’

H. M. Brown-Borg, S. G. Rakoczy, J. A. Wonderlich, L. Rojanathammanee, J. J. Kopchick, V. Armstrong, D. Raasakka 

Aging Cell, Volume 13, Issue 6, December 2014, Pages 1019-1027 

‘Maternal caloric restriction partially rescues the deleterious effects of advanced maternal age on offspring’ 

K. E. Gribble, G. Jarvis, M. Bock, D. B. M. Welch 

Aging Cell, Volume 13, Issue 4, August 2014, Pages 623-630

AGING CELL BEST PAPER PRIZE 2013

‘Calorie restriction in humans inhibits the P13/AKT pathway and induces a younger transcription profile’

E. M. Mercken, S. D. Crosby, D. W. Lamming, L. JeBailey, S. Krzysik-Walker, D. T. Villareal, M. Capri, C. Franceschi, Y. Zhang, K. Becker, D.M. Sabatini, R.de Cabo, L. Fontana

Aging Cell, Volume 12, Issue 4, August 2013, pp 645-651

To be presented  at the AS Winter meeting Birmingham, 15th to 16th December, ,2014

AGING CELL RUNNER-UP BEST PAPER PRIZES 2013

‘Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements’

M. De Cecco, S.W. Criscione, E.J.Peckham, S. Hillenmeyer, E.A. Hamm, J.Manivannan, A.L. Peterson, J.A. Kreiling, N. Neretti, J.M.Sedivy

Aging Cell, Volume 12, Issue 2, April 2013, pp 247-256

‘A metabolic signature predicts biological age in mice’

A. Tomás-Loba, B.B. de Jesus, J.M. Mato  and M.A. Blasco

Aging Cell, Volume 12, Issue 1, February 2013, pp 93-101

Winner 2012 Aging Cell Best Paper Prize

'Deviation of inate circadian Period from 24 h reduces longevity in mice'

Sergiy Libert, Michael S. Bonkowski, Kelli Pointer, Scott D. Pletcher and Leonard Guarente

Volume 11, Issue 5, October 2012, pp 794-799.

Then we have 2 Runner- Up Best Paper Prizes 2012 

‘A new role for laminins as modulators of protein toxicity in Caenorhabditis elegans’.

L. T.  Jensen, T. H.  Møller, S. A. Larsen, H. Jakobsen and A. Olsen

Volume 11, Issue 1, February 2012, pp 82-92

‘Temporal requirements of heat shock factor-1 for longevity assurance’

Y. Volovik, M. Maman, T. Dubnikov, M. Bejerano-Sagie, D. Joyce, E. A. Kapernick, E. Cohen and A. Dillin

Volume 11, Issue 3, June 2012, pp 491-499

Winner 2011 Aging Cell Best Paper Prize

The arcuate nucleus and neuropeptide Y contribute to the antitumorigenic effect of calorie restriction.

R. K. Minor, M. Lo´ pez, C. M. Younts, B. Jones, K. J. Pearson, R. Michael Anson, C. Die´guez and R. de Cabo.

Volume 10, Issue 3, June 2011,pp 483-492.

The picture on the right shows Robin Minor receiving the award from the President Prof. D. Ceri Davies at the Winter Meeting of the Society at the Royal Veterinary College London.

Robin Minor

Runner- Up Best Paper Prizes 2011

The Shc locus regulates insulin signaling and adiposity in mammals

A. A. Tomilov, J. J. Ramsey, K. Hagopian, M. Giorgio, K. M. Kim, A. Lam, E. Migliaccio, K. C. Lloyd, I. Berniakovich, T. A. Prolla, P. Pelicci and G. A. Cortopassi.

Volume 10, Issue 1, February 2011, pp 55-65

Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination

N. M. V. Gomes, O. A. Ryder, M. L. Houck, S. J. Charter, W. Walker, N. R. Forsyth, S. N. Austad, C. Venditti, M. Pagel, J. W. Shay and W. E. Wright.

Volume10, Issue 5, October 2011, pp 761-768

 

Aging Cell Best Paper Prize 2010 

The photograph shows Dr. Liao receiving his award from the President Professor D. Ceri Davies at the Cardiff Meeting in December 2011.

Dr. Liao

Aging Cell Runner-Up Best Paper Prizes 2010

The papers detailed below were judged by the editors of Aging Cell to merit the Aging Cell Runner-Up Best Paper Prize 2010. This Prize is awarded by the Anatomical Society's Prizes and Awards Committee, on the recommendation of the Editors-in-Chief of Aging Cell.

The annual prize for the best paper published in the journal Aging Cell in 2010 (Volume 9) has been awarded to Dr. Chen-Yu Liao and co-authors for their paper describing the "Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening".

PAPER  9(4) 626-635

‘Resistance to experimental tumorigenesis in cells of a long-lived mammal, the naked mole-rat (Heterocephalus glaber)’Sitai Liang, James Mele, Yuehong Wu, Rochelle Buffenstein and Peter J. Hornsby 

PAPER  9(2) 162-173

‘SIRT6 protects against pathological damage caused by diet-induced obesity’Yariv Kanfi, Victoria Peshti, Reuven Gil, Shoshana Naiman, Liat Nahum, Eran Levin, Noga Kronfeld-Schor and Haim Y. Cohen

Aging Cell Best Paper Prize 2009

The photograph shows Dr Ander Matheu (MRC National Institute for Medical Research, London) receiving the Aging Cell Best Paper Prize from Emeritus Professor Susan Standring at the Anatomical Winter Meeting held in the Gordon Museum at King’s College, London on Friday 17th December 2010.

The title of the Lecture: ‘Aging in mice with increased Ink4a/Arfand

Dr Ander Matheu