Aging Cell Best Paper Prize

Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity

Nelly Olova, Daniel J. Simpson, Riccardo E. Marioni,  Tamir Chandra

Aging Cell Joint Runner-Up Best Paper Prize

e12914 Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a

So-Jin Kim, Peiying Shan, Cheol Hwangbo, Yi Zhang, Jin-Na Min, Xuchen Zhang
Taylor Ardito, Alfred Li, Tien Peng, Maor Sauler, Patty J. Lee

Aging Cell, Volume 18, Issue 3, June 2019

Aging Cell. 2019;18:e12914     https://doi.org/10.1111/acel.12914

                                              and  

e12971 Restored immune cell functions upon clearance of senescence in the irradiated splenic environment

Lina Palacio, Marie-Lyn Goyer, Damien Maggiorani, Andrea Espinosa, Norbert Villeneuve, Sara Bourbonnais, Gaël Moquin-Beaudry, Oanh Le, Marco Demaria,
Albert R. Davalos, Hélène Decaluwe, Christian Beauséjour 

Aging Cell, Volume 18, Issue 4, August 2019

Aging Cell. 2019;18:e12971     https://doi.org/10.1111/acel.12971

                                              and

e13041 A human tissue-specific transcriptomic analysis reveals a complex relationship between aging, cancer, and cellular senescence

Kasit Chatsirisupachai, Daniel Palmer, Susana Ferreira, João Pedro de Magalhães

Aging Cell, Volume 18, Issue 6, December 2019 

Aging Cell. 2019;18:e13041  https://doi.org/10.1111/acel.13041

Aging Cell Best Paper Prize 2018

Replacement of microglia in the aged brain reverses cognitive, synaptic and neuronal deficits in mice

Monica R. P. Elmore, Lindsay A. Hohsfield, Enikö A. Kramár, Lilach Soreq, Rafael J. Lee, Stephanie T. Pham, Allison R. Najafi, Elizabeth E. Spangenberg, Marcelo A. Wood, Brian L. West, Kim N. Green

Aging Cell, Volume 17, Issue 6, December 2018, Pages 12832-12846

Aging Cell Best Paper Prize 2017

Kristen M. Stearns-Reider, Antonio D’Amore, Kevin Beezhold, Benjamin Rothrauff, Loredana Cavalli, William R. Wagner, David A. Vorp, Alkiviadis Tsamis, Sunita Shinde,
Changqing Zhang, Aaron Barchowsky, Thomas A. Rando, Rocky S. Tuan, Fabrisia Ambrosio

Volume 16, Issue 3, pages 518-528, June 2017

Aging Cell Joint Runner-Up Best Paper Prize 2017

Expansion of myeloid-derived suppressor cells with aging in the bone marrow of mice through a NF-κB-dependent mechanism 

Rafael R. Flores, Cheryl L. Clauson, Joonseok Cho, Byeong-Chel Lee, Sara J. McGowan, Darren J. Baker, Laura J. Niedernhofer, Paul D. Robbins

Volume 16, Issue 3, pages 480-487, June 2017

Translation fidelity coevolves with longevity

Zhonghe Ke, Pramit Mallik, Adam B. Johnson, Facundo Luna, Eviatar Nevo, Zhengdong D. Zhang, Vadim N. Gladyshev, Andrei Seluanov and Vera Gorbunova

Volume 16, Issue 5, pages 988-993, October 2017

Aging Cell Best Paper Prize 2016

Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: ‘reverse’ antagonistic pleiotropy?

Basisty, N., Dai, D.-F., Gagnidze, A., Gitari, L., Fredrickson, J., Maina, Y., Beyer, R. P., Emond, M. J., Hsieh, E. J., MacCoss, M. J., Martin, G. M. and Rabinovitch, P. S.

Volume 15, Issue 4, pages 634–645, August 2016

 
Dr Adam Taylor presenting Dr Nathan Basisty with his Aging Cell  Best Paper Prize 2016 Certificate at the AS Winter Meeting, Dundee, 2017

Aging Cell Runner-Up Best Paper Prizes 2016

Mitochondrial metabolites extend lifespan

Mishur,R. J., Khan, M., Munkácsy, E., Sharma, L., Bokov, A., Beam, H., Radetskaya, O., Borror, M., Lane, R., Bai, Y. and Rea, S. L. 

Volume 15, Issue 2, pages 336-348, April 2016

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of antiapoptotic factors

Zhu, Y., Tchkonia, T., Fuhrmann-Stroissnigg, H., Dai, H. M., Ling, Y. Y., Stout, M. B., Pirtskhalava, T., Giorgadze, N., Johnson, K. O., Giles, C. B., Wren, J. D., Niedernhofer, L. J., Robbins, P. D. and Kirkland, J. L. 

Volume 15, Issue 3, pages 428-435, June 2016

Aging Cell Best Paper Prize 2015

‘Acceleated epigenetic aging in Down syndrome’
Horvath, S., Garagnani, P., Bacalini, M. G., Pirazzini, C., Salvioli, S., Gentilini, D., Di Blasio, A. M., Giuliani, C., Tung, S., Vinters, H. V. and Franceschi, C.

Aging Cell, Volume 14, Issue 3, June 2015, pages 491-495

Aging Cell Runner-Up Best Paper Prizes 2015

‘A peroxiredoxin, PRDX-2, is required for insulin secretion and insulin/IIS-dependent regulation of stress resistance and longevity’

Oláhová, M. and Veal, E. A.  

Aging Cell, Volume 14, Issue 4,  August 2015, pages 558–568

‘The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs’ 
Zhu, Y., Tchkonia, T., Pirtskhalava, T., Gower, A. C., Ding, H., Giorgadze, N., Palmer, A. K., Ikeno, Y., Hubbard, G. B., Lenburg, M., O’Hara, S. P., LaRusso, N. F., Miller, J. D., Roos, C. M., Verzosa, G. C., LeBrasseur, N. K., Wren, J. D., Farr, J. N., Khosla, S., Stout, M. B., McGowan, S. J., Fuhrmann-Stroissnigg, H., Gurkar, A. U., Zhao, J., Colangelo, D., Dorronsoro, A., Ling, Y. Y., Barghouthy, A. S., Navarro, D. C., Sano, T., Robbins, P. D., Niedernhofer, L. J. and Kirkland, J. L. 

Aging Cell, Volume 14, Issue 4,  August 2015, pages 644–658

Aging Cell Best Paper Prize 2014

'Altered proteome turnover and remodelling by short-term caloric restriction or rapamycin rejuvenate the aging heart’ 

D.-F. Dai,P. P. Karunadharma, Y. A. Chiao, N. Basisty, D. Crispin, E. J. Hsieh, T. Chen, H. Gu, D. Djukovic, D. Raftery, R. P. Beyer, M. J. Maccoss, P. S. Rabinovitch

Aging Cell, Volume 13, Issue 3, June 2014, Pages 529–539

Dr. Dai receives his award from President Prof. T. Clive Lee at the Winter Meeting of the Society in Cambridge

Aging Cell Runner-Up Best Paper Prizes 2014

‘Growth hormone signaling is necessary for lifespan extension by dietary methionine’

H. M. Brown-Borg, S. G. Rakoczy, J. A. Wonderlich, L. Rojanathammanee, J. J. Kopchick, V. Armstrong, D. Raasakka 

Aging Cell, Volume 13, Issue 6, December 2014, Pages 1019-1027 

‘Maternal caloric restriction partially rescues the deleterious effects of advanced maternal age on offspring’ 

K. E. Gribble, G. Jarvis, M. Bock, D. B. M. Welch 

Aging Cell, Volume 13, Issue 4, August 2014, Pages 623-630

Winner 2012 Aging Cell Best Paper Prize

'Deviation of inate circadian Period from 24 h reduces longevity in mice'

Sergiy Libert, Michael S. Bonkowski, Kelli Pointer, Scott D. Pletcher and Leonard Guarente

Volume 11, Issue 5, October 2012, pp 794-799.

Then we have 2 Runner- Up Best Paper Prizes 2012 

‘A new role for laminins as modulators of protein toxicity in Caenorhabditis elegans’.

L. T.  Jensen, T. H.  Møller, S. A. Larsen, H. Jakobsen and A. Olsen

Volume 11, Issue 1, February 2012, pp 82-92

‘Temporal requirements of heat shock factor-1 for longevity assurance’

Y. Volovik, M. Maman, T. Dubnikov, M. Bejerano-Sagie, D. Joyce, E. A. Kapernick, E. Cohen and A. Dillin

Volume 11, Issue 3, June 2012, pp 491-499

Aging Cell Best Paper Prize 2010 

The photograph shows Dr. Liao receiving his award from the President Professor D. Ceri Davies at the Cardiff Meeting in December 2011.

Aging Cell Runner-Up Best Paper Prizes 2010

The papers detailed below were judged by the editors of Aging Cell to merit the Aging Cell Runner-Up Best Paper Prize 2010. This Prize is awarded by the Anatomical Society's Prizes and Awards Committee, on the recommendation of the Editors-in-Chief of Aging Cell.

The annual prize for the best paper published in the journal Aging Cell in 2010 (Volume 9) has been awarded to Dr. Chen-Yu Liao and co-authors for their paper describing the "Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening".

PAPER  9(4) 626-635

‘Resistance to experimental tumorigenesis in cells of a long-lived mammal, the naked mole-rat (Heterocephalus glaber)’Sitai Liang, James Mele, Yuehong Wu, Rochelle Buffenstein and Peter J. Hornsby 

PAPER  9(2) 162-173

‘SIRT6 protects against pathological damage caused by diet-induced obesity’Yariv Kanfi, Victoria Peshti, Reuven Gil, Shoshana Naiman, Liat Nahum, Eran Levin, Noga Kronfeld-Schor and Haim Y. Cohen

Aging Cell Best Paper Prize 2009

The photograph shows Dr Ander Matheu (MRC National Institute for Medical Research, London) receiving the Aging Cell Best Paper Prize from Emeritus Professor Susan Standring at the Anatomical Winter Meeting held in the Gordon Museum at King’s College, London on Friday 17th December 2010.

The title of the Lecture: ‘Aging in mice with increased Ink4a/Arfand