New Funded PhD Partnership with RNID (Royal National Institute for Deaf People)
The Anatomical
Society (AS) was pleased to announce our new partnership for 2022/23 with RNID
(Royal National Institute for Deaf People) to fund a PhD studentship focused on
the functional anatomy of deafness. In order to develop better treatments, we
need to improve our understanding of the anatomy of the entire auditory system
at all levels from system to intracellular, and at all stages of the lifespan
from development to ageing. The partnership aims to encourage excellent
students and supervisors to become involved in research to improve
understanding of how the functional anatomy of the ear impacts hearing. This is
an exciting new partnership for the Society. Moving forward, we will be
announcing new partnerships with other charities, using anatomical knowledge to
shed light on disease.
Following a rigorous application process, the RNID/AS are
delighted to announce the winning project:
Project title: Mechanisms of sensory loss in Neurofibromatosis Type 2
Significance of the research proposal in benefitting anatomical
sciences research and promoting the interests of the Anatomical Society: This project aims to gain a better
understanding of the anatomical relationships between glial cells and sensory
neurons, and how these regulate neuronal survival. We will study a model of
Neurofibromatosis Type 2 (NF2) as one such paradigm. It will employ high
resolution techniques such as confocal microscopy and transmission electron
microscopy to reveal the morphology, cell biology and physiology of mouse inner
ear Schwann cells and other cells that normally express the tumour suppressor
protein merlin, and determine the consequences of merlin loss in NF2. The project
will include an anatomical comparison of tissue pathologies in humans and mice
at the level of light microscopy. This work will provide a novel and detailed
morphological analysis of sensory epithelia of the inner ear. The nominated
student has already shown a flair for bench science within our lab. Given their
previous background and training we feel they have the potential to use these
techniques and study anatomical subjects throughout a career in science.